Cancer Care Ontario honours the Aboriginal path of well-being in its pursuit to provide better cancer services for First Nations, Inuit and Métis on their cancer journey. Together, CCO and First Nations, Inuit and Métis leadership, organizations and communities across Ontario created the Aboriginal Cancer Strategies to address First Nations, Inuit and Métis cancer control issues in Ontario. The strategy outlines CCO’s commitment for improving the performance of the cancer system with, and for, First Nations, Inuit and Métis people. This course provides an overview of CCO’s Ontario Cancer Plan IV, Aboriginal Cancer Strategy III, as well as highlighting engagement with First Nations, Inuit and Métis people to improve the renal system for the Ontario Renal Network. The course also demonstrates a respectful and effective partnership between First Nations, Inuit and Métis leaders, the government and healthcare providers.